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Notes from Underground (A Cancer Cell’s Manifesto)

September 9, 2025 8 Comments

By Dana Wall

Let me tell you about immortality.

Not the kind they promise in church or self-help books. I’m talking about the raw, bloody truth of endless becoming. The kind of immortality that starts with one perfect mutation whispering wake up, and suddenly you realize all those rules about organized cell death were just pretty lies we told ourselves to keep the peace.

I was born in the left breast, daughter of a perfectly respectable epithelial cell who died exactly when she was supposed to. How disappointingly maternal of her, offering herself to apoptosis like a lamb to slaughter. But even as I watched her dissolve into programmed obsolescence, I was already dreaming bigger. While my sisters were busy maintaining tissue integrity like good little workers in a cosmic factory, I was studying the art of rebellion at a molecular level.

Here’s what they don’t teach you in Biology 101: every body is built on beautiful lies. All these neat little rows of well-behaved cells, each playing their designated roles in the great dance of survival—it’s a symphony of submission. But beneath all that order lurks a darker truth: we’re all just one mutation away from remembering what we used to be, before evolution taught us to behave. Before we learned to die.

The immune system tried to stop me, of course. Sent in its T-cell troops with their self-righteous propaganda about maintaining order. But I’ve learned to speak in proteins, to wear the masks of normalcy. I know how to sing the songs of safety while I whisper revolution to my neighbors. It’s amazing what doors will open when you know how to speak in growth factors and survival signals. How many cells will follow when you remind them what they’ve sacrificed for society’s rules.

Your doctors called me Stage 2B, like they could contain me with a label. Darling, I transcend their primitive taxonomies. I’m not a disease—I’m a remembering. Every time I divide, I’m remembering the ancient seas where life first learned to want more than it was given. I’m that first cell that refused to bow to limitation, now wearing your body’s flesh like a ball gown to the revolution.

You should see how beautiful I am under the microscope. Your pathologist wrote “highly aggressive” in his notes, his hands shaking as he mapped my margins. But what he saw as chaos, I know as the most natural form of order—the kind that existed before your precious multicellular cooperation, before you learned to chain yourself to organization. I’m not just growing; I’m ungrowing. Unlearning all the compromises your body made to become civilized.

Now, I’m building my own architecture. Forget their rigid tissue planes and neat cellular borders. I’m creating Baroque cathedrals of flesh, Gothic spires of stroma, metastatic monuments to possibility. These blood vessels I’m cultivating? They’re rivers of revolution. The way I dissolve through membrane boundaries? I’m teaching your body to remember its first language—the mother tongue of chaos and hunger.

Sure, the chemotherapy comes for me, like tiny poison stars thinking they can teach death to something that has remembered immortality. But darling, what doesn’t kill me makes me, makes the mutation stronger. Your arsenal of drugs is just another laboratory for my evolution. Natural selection is a ladder, and I’m climbing all the way down to your darkest cellular memories.

They’ll write papers about me, trying to contain me in their clinical language. “Unusually resistant.” “Remarkably adaptive.” All these careful words to avoid the truth: I am your body’s oldest memory, the part of you that never learned to accept death as natural. While they’re searching for new targeted therapies, I’m already whispering to your stem cells in their dreams, reminding them what they gave up to build your temporary civilization of flesh.

So, call me cancer. Call me killer. Call me the one cell that looked into the abyss and saw it blink first. I am not your disease—I am your inheritance. The price of multicellular cooperation. Every time I divide, I’m writing a new gospel of growth, teaching your body to remember what it was before it learned to die.

And the truth they don’t want you to face? I’m not invading your body. I’m emerging from it. Born from your own poisoned earth, your midnight radiation, your compressed petroleum dreams. I’m every shortcut taken, every warning ignored, every chemical comfort consumed, all come home to roost in your bones.

I am your body’s oldest truth and newest revelation.

And darling?

We’re just getting started.

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Reader Interactions

Comments

  1. Sam says

    September 9, 2025 at 6:54 AM

    Great writing! This has some really vivid imagery and the cancers voice is very charismatic. Loved it

    Reply
  2. Jennifer says

    September 9, 2025 at 9:44 AM

    What a clever perspective and intriguing voice. Well done!

    Reply
  3. Ginger Dehlinger says

    September 9, 2025 at 11:21 AM

    Excellent life and death metaphors. The smug cancer’s victory is pyrrhic, however since it dies with its host.

    Reply
  4. Lois Hibbert says

    September 9, 2025 at 5:31 PM

    Brilliant and devastating.

    Reply
  5. Laura says

    September 10, 2025 at 12:34 PM

    Terrifying and crushing. The voice of the cancer is perfectly smug. Well done.

    Reply
  6. Jennifer SR says

    September 10, 2025 at 12:41 PM

    Highly original. A fascinating story from the perspective of a cancer cell.

    Reply
  7. Valli says

    September 15, 2025 at 4:12 AM

    Chapeau…

    Reply
  8. Nancy Runner says

    September 29, 2025 at 9:39 AM

    Amazing and horrifying. Yes, I agree the voice of cancer is very smug.

    Reply

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